Female antibodies to sperm

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30 Jan Antisperm antibodies aren't common. Both men and women can make them. They can make it harder for couples to have a baby. But it's rare.

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This study was performed to determine antisperm antibodies in cervicovaginal secretions and serum of infertile women and also measure serum levels of.

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Infertility Due to Anti-Sperm Antibodies in a Woman | Sher Fertility

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Description:Discussion Immunoinfertility is one of the major causes of infertility in humans which entails production of specific autoantibodies against sperm In this study, the percentages of ASAs were similar in cervicovaginal secretions This similarity between the two tests arises from the fact that indirect agglutination detects autoantibodies directed against surface sperm antigens while in indirect immunofluorescence method the internal sperm antigens are exposed after damage to the plasma membrane or use of methanol during fixation process. All these may lead to false positive results. In addition, cross-reactive antibodies may develop against exogenous antigens that react with sperm anti-gens. Furthermore, polyclonal B cell activation leads to formation of autoantibodies.

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